| Acronym | Meaning | Country |
| UA | Adventist University | Rwanda |
| UA | Uganda Army | Uganda |
| UA | Ugandan American | Uganda |
| UAACC | United African Alliance Community Center | Tanzania |
| UAC | Uganda AIDS Commission | Uganda |
| UAF | Uganda Athletics Federation | Uganda |
| UAH | Ugandans at Heart | Uganda |
| UAUT | United African University of Tanzania | Tanzania |
| UB | Université du Burundi | Burundi |
| UBA | Uganda Bankers Association | Uganda |
| UBA | United Bank for Africa | |
| UBC | Uganda Broadcasting Corporation | Uganda |
| UBL | Uganda Breweries Limited | Uganda |
| UBOS | Uganda Bureau of Statistics | Uganda |
| UBPR | Union des Banques Populaires du Rwanda | Rwanda |
| UBT | Ubungo Bus Terminal (Tanzania) | Tanzania |
| UBTEB | Uganda Business and Technical Examinations Board | Uganda |
| UBTS | Uganda Blood Transfusion Service | Uganda |
| UCA | Uganda Cooperative Alliance | Uganda |
| UCA | Uganda Cricket Association | Uganda |
| UCAA | Uganda Civil Aviation Authority | Uganda |
| UCB | Uchumi Commercial Bank | Tanzania |
| UCC | Uganda Communication Commission | Uganda |
| UCC | University Computing Center | Tanzania |
| UCC | Uganda Communications Commission | Uganda |
| UCCCU | Uganda Crane Creameries Cooperative Union | Uganda |
| UCDA | Uganda Coffee Development Authority | Uganda |
| UCE | Uganda Certificate of Education | Uganda |
| UCE | Uganda Commodity Exchange | Uganda |
| UCF | Uganda Chess Federation | Uganda |
| UCF | Uganda Conservation Foundation | Uganda |
| UCH | Uganda Chartered HealthNet | Uganda |
| UCI | Uganda Cancer Institute | Uganda |
| UCIFA | Uganda Clearing Industry and Forwarding... | Uganda |
| UCK | Université Catholique de Kabgayi | Rwanda |
| UCL | Uganda Clays Limited | Uganda |
| UCLAS | University College of Lands, Architecture and Surveys | Tanzania |
| UCMB | Uganda Catholic Medical Bureau | Uganda |
| UCMP | Uganda Chamber of Mines and Petroleum | Uganda |
| UCO | Uganda Country Office | Uganda |
| UCRT | Ujamaa Community Resource Team | Tanzania |
| UCS | Uganda Cancer Society | Uganda |
| UCSAF | Universal Communications Service Access Fund | Tanzania |
| UCSCU | Uganda Cooperative Savings and Credit Union | Uganda |
| UCSD | Uganda Coalition for Sustainable Development | Uganda |
| UCTF | Uganda Charity Trust Fund | Uganda |
| UCU | Uganda Christian University | Uganda |
| UDB | Uganda Development Bank | Uganda |
| UDC | Université des Collines | Burundi |
| UDC | Uganda Development Corporation | Uganda |
| UDC | Uganda Development Corporation | Uganda |
| UDEAC | Central African Customs and Economic Union | |
| UDF | Unified Democratic Forces | Rwanda |
| UDHR | Universal Declaration for Human Rights | |
| UDHS | Uganda Demographic Health Survey | Uganda |
| UDN | Uganda Debt Network | Uganda |
| UDOM | University of Dodoma | Tanzania |
| UDS | Uganda Development Services | Uganda |
| UDSM | University of Dar es Salaam | Tanzania |
| UDSM-IMS | University of Dar Es Salaam - Institute of Marine Sciences | Tanzania |
| UDSM-IRA | University of Dar Es Salaam - Institute of Resource Assessment | Tanzania |
| UEA | Université Espoir d'Afrique | Burundi |
| UEA | University of East Africa | Tanzania |
| UEAB | University of Eastern Africa, Baraton | Kenya |
| UEB | Uganda Electricity Board | Uganda |
| UEC | Uganda Episcopal Conference | Uganda |
| UEDCL | Uganda Electricity Distribution Company Limited | Uganda |
| UEEF | Uganda Environmental Education Foundation | Uganda |
| UEGCL | Uganda Electricity Generation Company Ltd | Uganda |
| UEPB | Uganda Export Promotion Board | Uganda |
| UETCL | Uganda Electricity Transmission Company Ltd | Uganda |
| UFA | Uganda Federal Alliance | Uganda |
| UFEA | Uganda Flower Exporters Association | Uganda |
| UFF | Uganda Film Festival | Uganda |
| UFF | Uganda Freedom Fighters | Uganda |
| UFL | University Football League | Uganda |
| UFM | Uganda Freedom Movement | Uganda |
| UG | University of Gitwe | Rwanda |
| UG | Uganda | Uganda |
| UGHE | University of Global Health Equity | Rwanda |
| UGL | Université des Grands Lacs | Burundi |
| UGO | Uganda Goes Online | Uganda |
| UGX | Ugandan Shilling | |
| UHI | Uganda Heart Institute | Uganda |
| UHRC | Uganda Human Rights Commission | Uganda |
| UHSC | Uganda Health Supply Chain | Uganda |
| UHTTI | Uganda Hotel and Tourism Training Institute | Uganda |
| UIA | Uganda Investment Authority | Uganda |
| UIA | Uganda Insurers Association | Uganda |
| UIA | Uganda Investment Authority | Uganda |
| UIBFS | Uganda Institute of Banking and Financial Services | Uganda |
| UIC | Uganda Insurance Commission | Uganda |
| UICT | Uganda Institute of Information & Communication Technology | Uganda |
| UIGF | Uganda Internet Governance Forum | Uganda |
| UIPE | Uganda Institution of Professional Engineers | Uganda |
| UIRI | Uganda Industrial Research Institute | Uganda |
| UIXP | Uganda Internet Exchange Point | Uganda |
| UJCC | Uganda Joint Christian Council | Uganda |
| UJU | Uganda Journalists Union | Uganda |
| ULA | Uganda Land Alliance | Uganda |
| ULBU | Université Lumière de Bujumbura | Burundi |
| ULC | Uganda Land Commission | Uganda |
| ULGA | Uganda Local Governments Associations | Uganda |
| ULII | Uganda Legal Information Institute | Uganda |
| ULK | Université Libre de Kigali | Rwanda |
| ULK | Kigali Independent University | Rwanda |
| ULRC | Uganda Law Reform Commission | Uganda |
| ULS | Uganda Law Society | Uganda |
| ULT | Université du Lac Tanganyika | Burundi |
| UM | Université de Mwaro | Burundi |
| UMA | Uganda Manufacturers Association | Uganda |
| UMBS | Uganda Muslim Brothers and Sisters | Uganda |
| UMDF | Uganda Media Development Foundation | Uganda |
| UMDPC | Uganda Medical and Dental Practitioners Council | Uganda |
| UMEA | Uganda Muslim Education Association | Uganda |
| UMI | Uganda Management Institute | Uganda |
| UMLK | Université Martin Luther King | Burundi |
| UMNP | Udzungwa Mountain National Park | Tanzania |
| UMSC | Uganda Muslim Supreme Council | Uganda |
| UMU | Uganda Martyrs University | Uganda |
| UMWA | Uganda Media Women Association | Uganda |
| UN | United Nations | |
| UN | United Nations (UN) | |
| UN Women | United Nations Entity for Gender Equality and the Empowerment of Women | |
| UNAA | Ugandan North American Association | Uganda |
| UNAB | Uganda National Association of the Blind | Uganda |
| UNABCEC | Uganda National Association of Building and Civil Engineering Contractors | Uganda |
| UNADA | Uganda National Agro-input Dealers Association | Uganda |
| UNAIDS | Joint United Nations Programme on HIV/AIDS | |
| UNAMIR | United Nations Assistance Mission in Rwanda | Rwanda |
| UNAP | Uganda Nutrition Action Plan | Uganda |
| UNAPD | Uganda National Action on Physical Disability | Uganda |
| UNAS | Uganda National Academy of Sciences | Uganda |
| UNAU | United Nations Association of Uganda | Uganda |
| UNBS | Uganda National Bureau of Standards | Uganda |
| UNBS | Uganda National Bureau of Standards | |
| UNC | Uganda National Congress | Uganda |
| UNCC | Uganda National Cultural Centre | Uganda |
| UNCCI | Uganda National Chamber of Commerce & Industry | Uganda |
| UNCHE | Uganda National Council of Higher Education | Uganda |
| UNCST | Uganda National Council for Science and Technology | Uganda |
| UNCT | UN Country Team | |
| UNDAF | UN Development Framework | |
| UNDAP | United Nations Development Assistance Plan | |
| UNDEP | United Nations Environment Program | |
| UNDF | United Nations Detention Facility | Rwanda |
| UNDP | United Nations Development Programme | |
| UNDP | United Nations Develop Programme | Uganda |
| UNDSS | United Nations Department of Safety and Security | |
| UNEB | Uganda National Examinations Board | Uganda |
| UNECA | United Nations Economic Commission for Africa | |
| UNEF | United Nations Emergency Force | |
| UNEP | United Nations Environmental Programme | |
| UNESCO | United Nations Educational, Scientific and Cultural Organization | |
| UNFA | Uganda National Farmers Association | Uganda |
| UNFPA | United Nations Population Fund | |
| UNG | Université de Ngozi | Burundi |
| UNGA | United Nations General Assembly | |
| UNHABITAT | United Nations Human Settlements Programme | |
| UNHAS | United Nations Humanitarian Air Service | |
| UNHCO | Uganda National Health Consumers Organization | Uganda |
| UNHCR | United Nations High Commissioner for Refugees | |
| UNHRO | Uganda National Health Research Organization | Uganda |
| UNHRO | Uganda National Health Research Organisation | Uganda |
| UNHS | Uganda National Household Survey | Uganda |
| UNIC | United Nations Information Centre | |
| UNICEF | United Nations Children's Fund | |
| UNIDO | United Nations Industrial Development Organization | |
| UNIIB | United Nations Independent Investigation on Burundi | Burundi |
| UNIK | University of Kibungo | Rwanda |
| UNILAK | University of Lay Adventists of Kigali | Rwanda |
| UNISE | Uganda National Institute of Special Education | Uganda |
| UNITAR | United Nations Institute for Training and Research | |
| UNJLC | United Nations Joint Logistics Centre | |
| UNMA | Uganda National Meteorological Authority | Uganda |
| UNMAS | United Nations Mine Action Services | |
| UNMC | Uganda Nurses and Midwives Council | Uganda |
| UNMHCP | Uganda National Minimum Health Care Package | Uganda |
| UNMIS | United Nations Mission in Sudan | |
| UNMU | Uganda Nurses and Midwives Union | Uganda |
| UNOCHA | United Nations Office for the Coordination of Humanitarian Affairs | |
| UNODC | United Nations Office on Drugs and Crime | |
| UNOMUR | United Nations Observer Mission in Uganda-Rwanda | Rwanda |
| UNR | Université Ntare Rugamba | Burundi |
| UNR | National University of Rwanda | Rwanda |
| UNR | Université Nationale du Rwanda | Rwanda |
| UNRA | Uganda National Roads Authority | Uganda |
| UNRA | Uganda National Roads Authority | Uganda |
| UNRF | Uganda National Rescue Front | Uganda |
| UNSECOORD | United Nations Security Coordinator's Office | |
| UNU | United Nations University (UNU) | |
| UNV | United Nations Volunteers | |
| UNWTO | World Tourism Organization (UNWTO) | |
| UoA | University of Arusha | Tanzania |
| UoB | University of Bagamoyo | Tanzania |
| UOB | Urwego Opportunity Bank | Rwanda |
| UOBDU | United Organisation for Batwa Development in Uganda | Uganda |
| UOC | Uganda Olympic Committee | Uganda |
| UoE | University of Eldoret | Kenya |
| UoEm | University of Embu | Kenya |
| UoI | University of Iringa | Tanzania |
| UoK | University of Kabianga | Kenya |
| UOK | University of Kigali | Rwanda |
| UoN | University of Nairobi | Kenya |
| UP | Umutara Polytechnic | Rwanda |
| UP(s) | Underlying Principle(s) | |
| UPC | Uganda Peoples Congress | Uganda |
| UPD | United Democratic Party (Tanzania) | Tanzania |
| UPD | Union for Peace and Development | Burundi |
| UPDA | Uganda People's Democratic Army | Uganda |
| UPDF | Uganda People's Defence Force | Uganda |
| UPDP | United Peoples Democratic Party | Tanzania |
| UPE | Universal Primary Education | Tanzania / Uganda |
| UPE | Universal Primary Education | Uganda |
| UPF | Uganda Police Force | Uganda |
| UPG | Université Polytechnique de Gitega | Burundi |
| UPK | Uganda Polytechnic Kyambogo | Uganda |
| UPL | Uganda Premeir League | Uganda |
| UPMB | Uganda Protestant Medical Bureau | Uganda |
| UPR | Université Paix et Reconciliation | Burundi |
| UPRS | Uganda Performing Right Society | Uganda |
| UPTC | Uganda Posts and Telecommunications Corporation | Uganda |
| UPU | Uganda Pentecostal University | Uganda |
| UQIS | Uganda Quarantine Inspection Services | Uganda |
| UR | University of Rwanda | Rwanda |
| URA | Ugandan revenue authority | Uganda |
| URC | Uganda Railways Corporation | Uganda |
| URC | Uganda Railways Corporation | Uganda |
| URC | Uganda Red Cross | Uganda |
| URCS | Uganda Red Cross Society | Uganda |
| URCSF | Uganda Rural Community Support Foundation | Uganda |
| URDT | Uganda Rural Development and Training | Uganda |
| URF | Uganda Road Fund | Uganda |
| URF | Uganda Rural Fund | Uganda |
| URHC | Uganda Refinery Holding Company | Uganda |
| URRO | Uganda Reproduction Rights Organisation | Uganda |
| URSB | Uganda Registration Services Bureau | Uganda |
| URSSI | Uganda Road Sector Support Initiative | Uganda |
| URT | United Republic of Tanzania | Tanzania |
| URU | Uganda Rugby Union | Uganda |
| US | Uganda Shilling | Uganda |
| USA | Uganda Society of Architects | Uganda |
| USAID | United StateS Agency for International Development | |
| USD | United States Dollar | |
| USD | United States Dollars | |
| USDC | Uganda Society for Disabled Children | Uganda |
| USE | Uganda Securities Exchange | Uganda |
| USE | Universal Secondary Education | Uganda |
| USH | University of the Sacred Heart Gulu | Uganda |
| USIU-Africa | United States International University | Kenya |
| USL | Uganda Super League | Uganda |
| USPA | Uganda Sports Press Association | Uganda |
| USSIA | Uganda Small Scale Industries Association | Uganda |
| UTA | Uganda Tourism Association | Uganda |
| UTAB | University of Technology and Arts of Byumba | Rwanda |
| UTAMU | Uganda Technology and Management University | Uganda |
| UTB | University of Tourism Technology and Business Studies | Rwanda |
| UTB | Uganda Tourist Board | Uganda |
| UTC | Union Trade Centre (Rwanda) | Rwanda |
| UTC | Uganda Technical College | Uganda |
| UTL | Uganda Telecom Ltd | Uganda |
| UTPC | Union of Tanzania Press Clubs | Tanzania |
| UTT | Unit Trust of Tanzania | Tanzania |
| UU | Umma University | Kenya |
| UVA | Uganda Veterinary Association | Uganda |
| UVF | Uganda Volleyball Federation | Uganda |
| UVP | Uganda Village Project | Uganda |
| UVP | Uganda Volunteers for Peace | Uganda |
| UVRI | Uganda Virus Research Institute | Uganda |
| UWA | Uganda Wildlife Authority | Uganda |
| UWA | Uganda Wildlife Authority | Uganda |
| UWEC | Uganda Wildlife Education Centre | Uganda |
| UWEC | Ugandan Wildlife Education Centre | Uganda |
| UYAFPAH | Uganda Youth Alliance for Family Planning... | Uganda |
| UYAHF | Uganda Youth and Adolescent Health Forum | Uganda |
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